Regenerative Medicine

Pain can be a constant companion dragging you down mentally and physically. Fortunately, the Pain Management and Anti-Aging Center can offer treatment that, in many cases, relieves or otherwise eliminates your chronic pain.

Is my pain a problem?

If moving in certain ways, participating in activities you used to enjoy, or merely performing the everyday physical requirements of your job results in stabbing, debilitating pain, you can easily and quickly become a slave to your pain. Whether it comes at the moment of activity, or later on - perhaps during the night while in bed, or the next morning when you experience difficulty rising, this pain, your constant companion, now defines the boundaries of your life.

Many remedies are used to treat such pain, including rest, medication, traction, exercise, cortisone injections, physical therapy, and surgery. In many cases, however, these treatments fail and you must seek an alternate way of gaining immediate, lasting relief.

Is there a therapy that will actually work?

Fortunately, there is a proven solution, Prolotherapy, or Reconstructive Injection Therapy. The Pain Management and Anti-Aging Center specializes in Prolotherapy. Learn more about this wonderful therapy in the next section. In addition to Prolotherapy, we cooperate with the primary care physician to provide you with a complete regimen of traditional and complementary medicines to treat "the whole patient." Therapies include:

  • Facet injections 

  • Effective pain relief during injections

  • Neural therapy 

  • Osteopathic manipulation

  • Epidural injections for relief of low back pain

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Pain Management


What is Prolotherapy?

Prolotherapy causes the proliferation, or growth, of new ligament tissue in areas where it has become stretched, torn, or otherwise weakened.


Ligaments and tendons are structures in the body that hold and support your joints. When the ligaments near a joint have not healed back to their original strength, the joint is not supported properly, and the result is usually chronic pain.  Prolotherapy uses a dextrose solution, which is injected into the ligament or tendon. The result is a localized inflammation which then increases the blood supply and stimulates the tissue to repair itself.

What types of problems can Prolotherapy treat?

Prolotherapy has consistently demonstrated its effectiveness in the treatment and cure of pain associated with:

  • Neck and back pain

  • Arthritis

  • Migraine and chronic headache

  • TMJ, neck pain, and whiplash

  • Shoulder, arm, and wrist pain

  • Carpal Tunnel and tennis elbow

  • Back and hip pain

  • Knee, ankle, and foot spurs

  • Heel spurs, arthritis, joint pain

  • Fibromyalgia

  • Loose tendons or ligament injury


Will Prolotherapy help me? How can I try it?

Prolotherapy is a specialty of the Pain Management and Anti-Aging Center. Dr. Allina evaluates each patient, and a plan is developed for your personal treatment. To find out if you will benefit from Prolotherapy, please contact us.

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Platelet rich plasma (PRP) therapy is a revolutionary new treatment that relieves pain by promoting long lasting healing of musculoskeletal conditions. This rapidly emerging technique is showing exciting potential with osteoarthritis of the knee, shoulder, hip and spine, rotator cuff tears, chronic plantar fasciitis, anterior cruciate ligament (ACL) injuries, pelvic pain and instability, back and neck injuries, tennis elbow, ankle sprains, tendonitis, and ligament sprains. Dr. Allina has been trained in Platelet Rich Plasma injection therapy (PRP) and has taught this procedure to physicians around the country.  He has performed the procedure on hundreds of patients and can determine if this advanced, non-surgical treatment is right for you.

How does PRP therapy help?
The body’s first response to soft tissue injury is to deliver platelet cells in the blood to the injured site. Packed with growth factors and healing factors, platelets initiate repair and attract the critical assistance of stem cells. PRP therapy’s natural healing process intensifies the body’s efforts by delivering a higher concentration of platelets to the site. To create PRP therapy, a small amount of your blood is drawn (similar to a lab test sample) and placed in a special machine called a centrifuge that spins the blood at high speeds, separating the platelets from the other components. The concentrated platelet rich plasma (PRP) is then injected into and around the point of injury, jump-starting and significantly strengthening the body’s natural healing signal. Because your own blood is used, there is no risk of a transmissible infection and a very low risk of allergic reaction.

How long does it take?
The procedure takes approximately one hour, including preparation and recovery time. Performed safely in our office, PRP therapy relieves pain without the risks of surgery, general anesthesia, or hospital stays and without a prolonged recovery. In fact, most people return to their jobs or usual activities soon after the procedure.

How often should this procedure be done?
The majority of patients only required one treatment to reach their goal of 85% to 100% pain relief.   The remainder required one or two more treatments spaced six to eight weeks later. You may, however, gain considerable to complete relief after the first or second injection.


What are the expected results?
Because the goal of PRP therapy is to resolve pain through healing, it could prove to have lasting results. Initial improvement may be seen within a few weeks, gradually increasing as the healing progresses. Research studies and clinical practice have shown PRP therapy to be very effective at relieving pain and returning patients to their normal lives. Both ultrasound and MRI images have shown definitive tissue repair after PRP therapy, confirming the healing process. The need for surgery can also be greatly reduced by treating injured tissues before the damage progresses and the condition is irreversible.


Make your appointment to see if you are a candidate for this exciting new procedure!  Take the next step to stop your pain and start living again.

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Platelet Rich Plasma (PRP)


What are Stem Cells?

Stem cells are undifferentiated cells that can self-replicate then develop into many different types of cells and tissue. Adult stem cells continuously divide and grow into new cells to repair and replace tissues that are old, damaged, or diseased.

There are different types of adult stem cells. Some produce one specific tissue, while others can replicate several types of cells. Stem cell therapy utilizes adult stem cells that can repair multiple tissues.

What is Stem Cell Therapy?

When a concentrated amount of stem cells are injected directly into damaged tissues, the stem cells regenerate and repair the damage by producing the new cells.

The stem cells used for your injection come from your own body. One type, mesenchymal cells, are particularly effective for orthopedic conditions and sports injuries because they regenerate cells common in musculoskeletal tissues, including bones, tendons, cartilage, and ligaments. Doctor Allina extracts adult mesenchymal stem cells from your abdominal adipose tissue and after processing and concentrating the stem cells, he injects them into the damaged tissues sometimes using ultrasound-guidance when indicated.

What Conditions are Treated with Stem Cell Therapy?

Stem cell therapy has successfully treated many orthopedic conditions, including tendon, ligament, and muscle injuries, joint damage, and nerve pain. These are just a few examples of health problems treated with stem cell therapy:

  • Rotator cuff tears

  • Osteoarthritis

  • Back and neck pain

  • Knee pain

  • Hand and wrist pain

  • Muscle, tendon, or ligament tears

  • Inflammatory problems like tendonitis and bursitis


As an expert in regenerative medicine, Doctor Allina is available to talk with you about stem cell therapy and how it may help your condition.

How Does PRP Therapy Complement Stem Cell Therapy?

Platelet-rich plasma (PRP) uses growth factors naturally found in your blood platelets to promote healing, trigger new tissue growth, and enhance the activity of stem cells. When your injury or disease is extensive, or you have degenerative joint disease, a tendon tear, or osteoarthritis, PRP will be added to your stem cell injection.


Like stem cell therapy, PRP is made on-site from your blood.  A sample of your blood is drawn and processed in a centrifuge that separates platelets from other blood components. This concentrated sample of platelets can be combined with your stem cell injection for accelerated healing.

If you’re not getting the results you want from your current treatment, it may be time to consider stem cell therapy. Call The Pain Management and Anti-Aging center for an appointment.

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Stem Cell Therapy


What are Exosomes?
Exosomes are so-called extracellular vesicles, or small bubbles, released from cells, especially from stem cells. They act as shuttles for certain genetic information and proteins to other cells. They allow for cell-to-cell communication, transporting molecules that are important regulators of intracellular information between close and distant cells. They carry information from place to place with different functions and purposes, telling cells how and when to react.

Exosomes are being heralded as the next frontier of cell therapy. While not being cells at all, they play a vital role in the communication and rejuvenation of all the cells in our body. Science has shown that the cell-to cell communication is important in maintaining a healthy cellular terrain. Age, chronic disease, environmental factors and genetic disorders can interfere with how our stem cells communicate with other cells, thus disrupting the healing process. Exosomes play a key role in the regulation of these communication processes.

What Is Exosome Therapy?
Research has given us a valuable insight into the practical functionality of exosomes. By exposing the cells of an older organism to those of a younger organism we can see that exosomes from the young stem cells are responsible for rejuvenating the older cells. This healing mechanism can now be used in regenerative medicine.


A degenerative disease comes from a continuous deterioration of cells, affecting tissues or organs. While stem cells are usually responsible for the rejuvenation of the cells, external factors may hinder the stem cells in this function. They may not be able to supply all the information needed. Supporting their function with external exosomes could have a greater positive effect, by providing new pieces of information to support the healing process.

Who May Benefit from Exosome Therapy?
Exosomes may help regulate processes within the body. Patients with Lyme disease, chronic inflammation, autoimmune disease and other chronic degenerative diseases may benefit from including exosomes in their
treatment regimen. Exosomes may also be beneficial as part of an anti-aging therapy. Patients with degenerative joint disease have also benefited from the use of exosomes.

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Exosome Therapy


Other Services

We have a passion for helping pilots stay safe in the skies! Dr. Allina has been serving the aviation community in this way since 1977. We've simplified this process into a few easy steps: 



Determine what type of Medical you need. This varies a bit depending on what type of flying you are doing. 

1st Class Medical Exam

A 1st class medical certificate is needed if you are a professional pilot exercising the privileges of your Airline Transport Pilot certificate.

2nd Class Medical Exam

You'll want to apply for a 2nd class medical certificate if you are a commercial pilot and are getting paid to fly airplanes.

3rd Class Medical Exam

The 3rd class medical certificate is required for student and private pilots when they are acting as Pilot In Command. If you fly for business or pleasure, this is most likely the certificate for you!


Fill out your MedXPress form. You'll need to create an account and complete this form before coming in for your exam. It's usually best to print out the competed form as well. At the very least, we'll need your confirmation number to find your form in our system. 


Call the office and schedule your exam! +1 (260) 434-1619

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FAA Medical Exam


American Association of Orthopaedic Medicine: Las Vegas, Nevada

  • The Connective Tissues: Their Function, Pathology, and Treatment

  • Estrogen and Progesterone Replacement Therapy In An Anti-Aging Practice

American Association of Orthopaedic Medicine: Orlando, Florida

  • Putting the Pieces Together: Hormones, Thyroid, Leaky Gut, and Prolotherapy

Association of periOperative Registered Nurses: Lutheran Hospital, Kachmann Auditorium

  • Wellness Medicine: Hormone Replacement, Leaky Gut, and Non-Surgical Pain Management

Safety Seminar: Smith Field Airport, Fort Wayne, IN

  • Stress and Flying

American Association of Orthopaedic Medicine: Millennium Knickerbocker Hotel, Chicago, IL

  • Hormones and Healing

  • Hormones and Healing Workshop

  • Stress and the Adrenal Gland

  • Steroid Hormone Assessment for Men and Women

Cameron Hospital: Angola, Indiana

  • Anti-Aging Considerations

Indiana Physical Therapy Association - Northeastern District

  • Introduction to Prolotherapy

Spiece 2005 Lifestyle Medical Center

  • The Prevention of Premature Aging: A Common Sense Approach to Integrated Holistic Medicine for the 21st Century

  • Natural Thyroid Replacement Therapy In An Anti-Aging Practice

American Association of Orthopaedic Medicine: Kansas City, MO

  • Hormonal Support

American College of Osteopathic Sclerotherapeutic Pain Management

  • Anti-Aging Considerations

  • Ligament and Tendon Reconstruction Injection Therapy for the Foot and Ankle

Indiana University - Purdue University Pre-Med Club: Fort Wayne, IN

  • Becoming an Osteopathic Physician

  • Hormone Essentials for Women


  • A Spoonful of Sugar Helps the Medicine Go Down

American Association of Orthopaedic Medicine: Las Vegas, NV

  • Seminar Overview

Urgent Care Center: Library Angola, IN

  • Anti-Aging with Bio-Identical Hormone Replacement

Indiana Osteopathic Association: Merriville, IN

  • Anti-Aging Therapies for the 21st Century

American Association of Orthopaedic Medicine: The Broadmoor Hotel, Colorado Springs, CO

  • Stress and the Adrenal Gland: Indications and Uses of Cortisol

  • Lab Test Data Explained

American College of Osteopathic Sclerotherapeutic Pain Management

  • Prolotherapy of the Knee

Rotary International: Fort Wayne, IN

  • Anti-Aging with Bio-Identical Hormone Replacement


  • Pain Management and Anti-Aging Center Overview

American Association of Orthopaedic Medicine: Las Vegas, NV

  • How to Improve Your Reconstruction Injection Therapy Results

American College of Osteopathic Sclerotherapeutic Pain Management: San Diego, CA

  • Ligament and Tendon Reconstruction Injections of the Knee Complex

Mary Kay: Fort Wayne, IN

  • Anti-Aging in the 21st Century

Rotary International: Fort Wayne, IN

  • Anti-Aging in the 21st Century

Surface Salon and Spa: Fort Wayne, IN

  • Anti-Aging in the 21st Century

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Informative Professional Presentations by Dr. Alfred F Allina